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Solution reagent AD189
for clinical chemistryaldolase

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Characteristics

Type: solution
Applications: for clinical chemistry
Tested parameter: aldolase

Description

A correlation coefficient of r=0.9917 was displayed when the Randox methodology was compared against commercially available methods. Measuring Range The Randox Aldolase assay has a measuring range of 1.73 – 106U/l for the comfortable detection of clinically important results. Lyophilised Reagents Lyophilised reagents offer enhanced stability, reducing wastage. Excellent Precision The Randox assay displayed a within run precision < 4.47% CV. Dedicated Calibrator and Controls Available Randox offer a dedicated Aldolase calibrator and controls for a complete testing package. Applications Available Applications available detailing instrument-specific settings for the convenient use of the Randox Aldolase assay on a variety of clinical chemistry analysers. Clinical Significance Elevated levels of aldolase are detected in myotonic muscular disease, including: polymyositis and progressive muscular dystrophy. Elevated levels of this enzyme have been observed in acute coronary syndromes 1. This enzyme has been identified as a myositis biomarker, a muscle-wasting disease resulting in reduced muscle strength and fatigue 2. Testing this enzyme can be utilised as a marker in the differential diagnosis of muscle weakness as aldolase levels remain consistent where weakness is caused by neurological problems such as multiple sclerosis (MS) 3. Physiological Significance Aldolase is a glycolytic enzyme responsible for catalysing the conversion of fructose 1-6-diphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate via the glycolysis metabolic pathway. This enzyme is present in all bodily cells, more commonly in the nucleus and cytoplasm.

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MEDICA 2024

11-14 Nov 2024 Düsseldorf (Germany) Hall 3 - Stand A08

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Go to the Randox Laboratories website for more information

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Solution reagent AD189for clinical chemistryaldolase

Characteristics

Description

Catalogs

Exhibitions

Other Randox Laboratories products

Diagnostic Reagents

Solution reagent AD189
for clinical chemistryaldolase