Enzyme reagent LP3866
immunoturbidimetricfor clinical chemistryliquid

Enzyme reagent - LP3866 - Randox Laboratories - immunoturbidimetric / for clinical chemistry / liquid
Enzyme reagent - LP3866 - Randox Laboratories - immunoturbidimetric / for clinical chemistry / liquid
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Characteristics

Type
enzyme
Applications
immunoturbidimetric, for clinical chemistry
Format
liquid
Tested parameter
lipoprotein, for apolipoproteins, lipid, genetic, triglycerides, bilirubin

Description

The immunoturbidimetric method limits interference from Bilirubin, Haemoglobin, Intralipid® and Triglycerides, producing more accurate results. Exceptional correlation A correlation coefficient of r=1.00 was displayed when the Randox apo C-II assay was compared to commercially available methods. Excellent measuring range The Randox apo C-II assay has a measuring range of 1.48 – 9.70mg/dl for the comfortable detection of clinically important results. Liquid ready-to-use The Randox apo C-II assay is available in a liquid ready-to-use format for convenience and ease-of-use. Dedicated calibrator and controls available Randox offer dedicated apolipoprotein calibrator and controls for a complete testing package. Applications available Applications available detailing instrument-specific settings for the convenient use of the Randox apo C-II assay on a variety of clinical chemistry analysers. PHYSIOLOGICAL SIGNIFICANCE Apo C – II is a 79-amino acid protein synthesised in the liver and is the co-factor for lipid transport in the bloodstream 1. Apo C – II is a surface constituent of lipoproteins and the C – terminal helix activates lipoprotein lipase (LPL) 2. The active peptide of apo C – II corresponds to residues 44 – 79 and has been identified to reverse the symptoms of genetic apo C – II deficiency. Moreover, LPL is also a key enzyme in the regulation of triglyceride levels 3. CLINICAL SIGNIFICANCE Both an excess and deficiency of apo C – II is associated with hypertriglyceridemia and reduced LPL activity. Elevated levels of apo C-II is associated with excess triglyceride – rich particles and altercations in the distribution of HDL particles,

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