Enzyme reagent BR series
for clinical chemistryliquidmyoglobin

enzyme reagent
enzyme reagent
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Characteristics

Type
enzyme
Applications
for clinical chemistry
Format
liquid
Tested parameter
myoglobin, iron, total bilirubin

Description

The Randox bilirubin assay has a correlation coefficient > 0.99% CV when compared to commercially available methods. Direct-Total Direct & Total assays available Randox offer both direct & total bilirubin assays offering choice and flexibility. Liquid ready-to-use The Randox bilirubin assay is available in a liquid ready-to-use format for convenience and ease-of-use. Calibrator & Controls Calibrator and dedicated control available Calibrator and dedicated control available offering a complete testing package. Applications available Applications available detailing instrument-specific settings for the convenient use of the Randox bilirubin assay on a variety of clinical chemistry analysers. PHYSIOLOGICAL SIGNIFICANCE - - - Bilirubin is a metabolite of haem, derived from haem-containing proteins, including myoglobin, haemoglobin and various P450 enzymes, that serves to coordinate iron in various proteins. Half of it is excreted into bile and the rest contributes to blood bilirubin turnover 1. It is mainly produced in the spleen and liver but can also occur elsewhere in the body by macrophages and renal tubular cells 2. The internal hydrogen bonding causes it to be water-insoluble and so required enzyme-mediated glucuronidation in the liver for biliary excretion. Under normal conditions, it is mostly unconjugated and bound tightly to albumin CLINICAL SIGNIFICANCE Bilirubin is a metabolite of haem, derived from haem-containing proteins, including myoglobin, haemoglobin and various P450 enzymes, that serves to coordinate iron in various proteins. Half of it is excreted into bile and the rest contributes to blood bilirubin turnover 1.

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Exhibitions

Meet this supplier at the following exhibition(s):

MEDICA 2024
MEDICA 2024

11-14 Nov 2024 Dusseldorf (Germany) Hall 3 - Stand A08

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