The Randox CK-MB reagent is available in a liquid ready-to-use or in a lyophilized format offering you convenience and choice when selecting the best choice for your laboratory
Other features of the Randox CK-MB reagent
Immunoinhibition UV method
Instrument Specific Applications (ISA’s) are available for a wide range of biochemistry analysers. Contact us to enquire about your specific analyser.
What is the CK-MB assay used for?
What is CK-MB?
Creatine Kinase (CK) is internationally accepted as a sensitive and specific indicator of acute myocardial infarction (AMI). There are 3 major forms of the iso-enzymes of CK, CK-MM, CK-MB and CK-BB. CK-BB is produced by the brain in very small insignificant amounts. CK-MM is produced by the skeletal and heart tissue. CK-MB is produced by the heart muscle and increases when the heart muscle is damaged. For more information on the structure and function of CK isoenzymes in tissue, please click here.
What is the CK-MB assay used for?
CK-MB is a more sensitive marker to myocardial infarction than total CK activity as CK-MB has a lower basal level and a narrower normal range. In the vast majority of cases the CK-MB activity rises within 4 to 6 hours of an acute infarction. Between 10 to 24 hours, maximum values are observed. The CK-MB activity generally returns to normal between the third and fourth day post- infarction.