Cytokine reagent CP7950
phagocytosisfor clinical chemistryliquid

Cytokine reagent - CP7950 - Randox Laboratories - phagocytosis / for clinical chemistry / liquid
Cytokine reagent - CP7950 - Randox Laboratories - phagocytosis / for clinical chemistry / liquid
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Characteristics

Type
cytokine
Applications
phagocytosis, for clinical chemistry
Format
liquid
Tested parameter
CRP, C-reactive protein, triglycerides, bilirubin
Storage temperature

Max.: 8 °C
(46 °F)

Min.: 2 °C
(36 °F)

Description

The Randox CRP assay has shown to have limited interference from conjugate and free bilirubin, haemoglobin, Intralipid® and triglycerides. Liquid ready-to-use The Randox CRP assay is available in a liquid ready-to-use format for convenience and ease-of-use. Applications available Applications available detailing instrument-specific settings for the convenient use of the Randox CRP assay on a variety of clinical chemistry analysers. Calibrator & Controls Dedicated calibrator and controls available Dedicated CRP calibrator and controls available offering a complete testing package. PHYSIOLOGICAL SIGNIFICANCE C-reactive protein (CRP) is the dominant acute phase protein in mammals 1. Elevated levels of CRP are not disease specific but are synthesised, by hepatocytes, in response to pro-inflammatory cytokines during inflammatory and/or infectious processes 2, 3. The physiological function of CRP is the enhancement of cell-mediated immunity through the promotion of phagocytosis, accelerated chemotaxis and the activation of platelets 1. Known as a biomarker of acute inflammation, many large-scale prospective studies demonstrate the association between CRP and chronic inflammation, including: cardiovascular disease (CVD), cerebrovascular accident (CVA) (ischaemic stroke), Alzheimer’s Disease, and age-related macular degeneration CRP is a major cardiovascular disease (CVD) risk factor. A CRP level of >10mg/l correlates with a >4% risk of developing a fatal CVD event in 10 years, including: myocardial infarction, peripheral arterial disease, stroke and sudden cardiac death. Inflammation is an integral part in the development

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