Solution reagent CYS4004
for clinical chemistryproteincystatin C

Solution reagent - CYS4004 - Randox Laboratories - for clinical chemistry / protein / cystatin C
Solution reagent - CYS4004 - Randox Laboratories - for clinical chemistry / protein / cystatin C
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Characteristics

Type
solution
Applications
for clinical chemistry
Tested parameter
protein, cystatin C, creatinine

Description

A correlation coefficient of r=1.00 was displayed when the Randox methodology was compared against commercially available methods. Precision Excellent Precision The Randox Cystatin C assay displayed a within run precision of < 4.2%. Measuring range Wide Measuring Range The Randox Cystatin C assay has a measuring range 0.4 – 10mg/l for the comfortable detection of clinically important results. Calibrator & Controls Dedicated Cystatin C Calibrator and Controls Dedicated Cystatin C Calibrator and Controls available offering a complete testing package. Applications Available Applications available detailing instrument-specific settings for the convenient use of the Randox cystatin C assay on a variety of clinical chemistry analysers. TRADITIONAL CKD BIOMARKERS Serum creatinine (SCr) is the most commonly utilised screening test for renal impairment; however, SCr can be affected by age, dietary protein intake, ethnicity, gender, and lean muscle mass. Consequently, the sensitivity of SCr for the early detection of kidney disease is poor and not suitable for the renal assessment in the elderly 1. The biggest drawback of SCr is that up to 50% of renal function can be lost before significant SCr levels become detectable as SCr is insensitive to small changes in GFR. Consequently, treatment is not provided at the appropriate time which can be fatal, and so an earlier and more sensitive biomarker for renal function is imperative Cystatin C (CysC) is a low-molecular-weight (13.3kDa) non-glycosylated protein belonging to the cystatin protease inhibitor family 2, 3. Formed at a constant rate by all nucleated cells,

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