Solution reagent RB series

for clinical chemistryD-3-hydroxybutyrate

The commercially available nitroprusside method is a semi-quantitative dipstick test which only detects acetone and acetoacetate. As the most abundant ketone produced during ketosis, D-3-hydroxybutyrate is more sensitive and specific. Correlation Exceptional correlation A correlation coefficient of r=0.9954 was displayed when the Randox method was compared against other commercially available methods. Precision Excellent precision The Randox Ranbut assay displayed an excellent precision of <3.5%. Calibrator & Control Calibrator and controls available Calibrator and controls are available offering a complete testing package. Applications available Applications available detailing instrument-specific settings for the convenient use of the Randox Ranbut assay on a variety of clinical chemistry analysers. Ketosis is a metabolic process that occurs when the body switches from glucose to predominantly fat metabolism for energy production, this happens when carbohydrate availability reaches low levels. The metabolism of fatty acids in the liver results in the production of chemical by-products known as ketone bodies or ketones. Ketosis occurs when the body produces more ketones than the liver can process. DKA is a serious complication of both Type I Diabetes Mellitus (T1DM), however can also affect individuals with T2DM. The condition is linked to insulin deficiency and occurs when glucose levels are consistently high and insulin levels are severely low. Due to this imbalance glucose builds up in the blood and the body responds by metabolising fat rather than glucose. DKA is usually one of the first indicators of T1DM.