The IgA assay showed a precision of less than 3% CV
Exceptional correlation
The assay showed a correlation of r=0.98 against another commercially available method
Interference
There is no cross reaction with IgG and IgM under the conditions of the assay. Extremely lipaemic or haemolytic samples and high levels of ionic detergents may interfere in the assay
Other features
Immunoturbidimetric method
Liquid ready-to-use reagents
What is IgA assay used for?
Measurement of IgA is used to diagnose diseases of the respiratory tract e.g. tuberculosis, Crohn’s disease and early cirrhosis of the liver. It is also useful in monitoring therapy of IgA myeloma and evaluating IgA immunity. IgA in colostrum and milk is important in neonatal defence against infection.
The Randox IgA assay is an immunoturbidimetric end-point method for manual use and on automated analysers. The increase in turbidity in a sample containing human IgA is measured at 340 nm. By constructing a standard curve from the absorbances of standards, the IgA concentration of a sample can be determined.