Lipoprotein reagent LP2757
solutionlaboratoryliquid

Lipoprotein reagent - LP2757 - Randox Laboratories - solution / laboratory / liquid
Lipoprotein reagent - LP2757 - Randox Laboratories - solution / laboratory / liquid
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Characteristics

Type
solution
Applications
laboratory
Format
liquid
Tested parameter
lipoprotein, lipid

Description

The Randox Lp(a) assay is calibrated in nmol/l and traceable to the WHO/IFCC reference material (IFCC SRM 2B) and provides an acceptable bias compared with the Northwest Lipid Metabolism Diabetes Research Laboratory (NLMDRKL) gold standard method. Dedicated five-point calibrator available Five-point calibrator with accuracy-based assigned target values (in nmol/l) is available, accurately reflecting the heterogeneity of the apo(a) isoforms. Dedicated Lp(a) control is available offering a complete testing package. Excellent correlation A correlation coefficient of r=0.995 was displayed when the Randox method was compared against other commercially available methods. Precision Excellent precision The Randox Lp(a) assay displayed a within run precision of <2.54%. Liquid ready-to-use The Randox Lp(a) assay is available in a liquid ready-to-use format for convenience and ease-of-use. Applications available Applications are available detailing instrument-specific settings for the convenient use of the Randox Lp(a) assay on a wide range of clinical chemistry analysers. The biggest challenge that exists surrounding Lp(a) measurement is the heterogeneity of the apo(a) isoforms, resulting in the underestimation or overestimation of Lp(a) concentrations. In immunoassays, the variable numbers of repeated KIV-2 units in Lp(a) act as multiple epitopes. This is where standardisation across calibrators is vital. Unless the calibrants do have the same range of isoforms as test samples, those with higher numbers of the KIV-2 repeat, will represent with an overestimation in Lp(a) concentrations

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