The TIBC assay showed a correlation coefficient of 0.9 against another commercially available method
Eliminates negative bias
Traditional calculation methods using the unsaturated iron-binding capacity (UIBC) and serum iron (TIBC = UIBC + serum iron) have a significant negative bias compared with direct TIBC methods. Randox’s TIBC assay eliminates this bias
Excellent precision
The TIBC assay has a precision of less than 4% CV
Randox Total Iron Binding Capacity (TIBC) (Colorimetric)
Colorimetric method
Liquid ready-to-use reagents
Eliminates negative bias
Minimal interferences
What is Total Iron Binding Capacity (TIBC) assay used for?
Iron is transported in the blood by the serum protein transferrin. Transferrin is normally 30% saturated, that is 30% of the iron-binding sites contain an iron atom. The total iron-binding capacity (TIBC) is the amount of iron needed to 100% saturate transferrin. TIBC reflects iron status: levels are elevated when iron levels are low; therefore it is useful in the diagnosis and monitoring of iron deficiency anaemia and iron deficiency in late pregnancy. Abnormal levels of TIBC can point towards a variety of disease states such as hereditary haemochromatosis, a common genetic disorder where iron levels are excessive, other anaemias, liver disease and malnutrition.