SPLA2-IIA reagent PLA8380
solutionapoptosisimmunoturbidimetric

SPLA2-IIA reagent - PLA8380 - Randox Laboratories - solution / apoptosis / immunoturbidimetric
SPLA2-IIA reagent - PLA8380 - Randox Laboratories - solution / apoptosis / immunoturbidimetric
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Characteristics

Type
solution
Applications
apoptosis, immunoturbidimetric
Format
liquid
Tested parameter
sPLA2-IIA, lipid, phospholipids

Description

A niche assay from Randox which means that Randox is one of the only manufacturers to offer an sPLA2-llA mass assay in an automated biochemistry format Applications available detailing instrument-specific settings for the convenient use of the Randox sPLA2-IIA assay on a wide range of clinical chemistry analysers Complementary controls and calibrators available offering a complete testing package Automated assay which removes the inconvenience and time consumption associated with traditional ELISA based testing Excellent correlation coefficient of r = 0.95 when compared against other commercially available methods Liquid ready-to-use format for convenience and ease of use Latex enhanced immunoturbidimetric method delivers high performance and confidence in results Clinical Significance sPLA2-llA production of fatty acids and biologically active phospholipids plays an important role in platelet, monocyte, and endothelial activation, processes known to be critical steps in atherogenesis.1 Unlike traditional cardiac biomarkers used to predict adverse outcomes in patients with acute coronary syndrome (ACS), sPLA2-llA has been shown to act at multiple pathways involved in atherogenesis, from lipid oxidation to modulation of vascular & inflammatory cell activation and apoptosis.2 Biological Significance of sPLA2-IIA Key observations through research has found that sPLA2-llA mediated modification of lipoproteins plays a role in the development of atherosclerosis.

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