Solution reagent kit KAPA HyperCap

for researchSARS-COV-2

For Research Use Only. Not for use in diagnostic procedures. KAPA HyperCap SARS-CoV-2 Target Enrichment Panel Sequence the SARS-CoV-2 genome for viral surveillance, evolution and detection of emerging1 new isolates or strains, by using the KAPA HyperCap SARS-CoV-2 target enrichment Panel. Prepare libraries from input RNA using the robust KAPA RNA HyperPrep Kit and then enrich for viral sequences; this panel targets 100% of the reference SARS-CoV-2 genome (NC_045512) and >99.7% of another 183 publicly available SARS-CoV-2 genomes. Identify multiple variants of SARS-CoV-2 in a single tube workflow* Cover about 97% of the SARS-CoV-2 genome by 1x down to 1000 viral copies, as few as 10 viral copies are enough to retrieve genome reads (in 20 ng or 100 ng universal human reference RNA background with 0.5 million 2 x 75 bp clusters) Report your results faster with hybridization in as short as 1 hour Cover more of the SARS-CoV-2 genome & identify viral sequence from low viral copy numbers The KAPA HyperCap SARS-CoV-2 Target Enrichment Panel achieves 1X coverage of ~97% of the SARS-CoV-2 genome down to 1000 viral copies and captures genomic sequence from as few as 10 viral copies. Samples containing the indicated number of viral copies in a background of either 20 ng (blue) or 100 ng (green) of human RNA background were processed in triplicate using KAPA RNA HyperPrep Kit and the KAPA HyperCap SARS-CoV-2 Target Enrichment Panel. Datasets were downsampled to 0.5 million clusters 2 x 75 bp prior to analysis