Macromolecule purification is critical in many life science workflows. However, resin-based ion exchange or affinity chromatography methods typically require sophisticated equipment and long set-up times, exhibit low flow rates, and suffer from limited yields. The small pore sizes and large bed volumes of conventional columns contribute to size exclusion and dilution effects, which limit the ability to purify larger macromolecules, demand further process steps to concentrate dilute eluates and increase reagent consumption. Furthermore, these purification processes are difficult to transfer to manufacturing.
Off-the-Shelf Consistency
Ready-to-use single use or reusable purification consumables provide highly reproducible results without being susceptible to dissolved air. No more column packing. Bye-bye degassing.
Your Choice for High Yields
Multiple chromatography methods with maximum dynamic binding capacities. Even the largest molecules can fully utilize the high density of ion exchange or affinity ligands.
Purification in Parallel
By purifying two, four, six or even 24 samples simultaneously with Vivapure® IEX, you can cut your already shortened process time even further. Full screen ahead.
75% Buffer Savings
Cut down on reagent consumption and waste. Low bed volumes only need a fraction of the buffers used in resin-based chromatography for equilibration, washing and elution.
Rapid affinity purification for IgGs and mAbs, with a process-ready protein A membrane.
10x faster flow rates, up to 5 MV/min
Operate by syringe, pump or FPLC system
90 mg/hr DBC (6 cycles)
Top Features of Sartobind® Lab Protein A Membrane Adsorbers