LC-MS/MS assay development can be challenging, particularly for analytes that coelute with contaminants or become buried within background noise. The SCIEX SelexION Differential Mobility Separation device (DMS) provides an extra level of selectivity so you can resolve difficult analytes and achieve higher confidence in detection and quantitation. Designed to install between the ionization source and the vacuum interface of your mass spectrometer, SelexION provides a further degree of separation beyond retention time and mass. SelexION uses gas phase differential ion mobility to enable the separation of coeluting compounds, isobaric and isomeric compounds, and compounds buried within high background noise. Instead of spending more time on LC separation strategies and sample preparation, SelexION simplifies your workflow with an innovative add-on separation solution. The SelexION Differential Mobility Separation device:
Provides a robust and reproducible additional level of selectivity and separation
Installs and de-installs within 2 minutes without breaking vacuum
Can be operated in a transparent mode for those assays where ion mobility is not required
Can be used with optional chemical modifiers to further increase separation power
Compatible with select SCIEX Triple Quad™, QTRAP®, and TripleTOF® Systems
Compatible with a variety of ion sources including the NanoSpray ion source and the Turbo V™ ion source
Compatible with fast UHPLC timescales
SelexION can enhance analyte detection, improve quantitation limits, simplify sample
preparation, and shorten assay development time. With applications in food and environmental analysis, forensics, lipidomics,