The simple three-channel nose-only drug delivery system is often used for animal model establishment and aerosol drug delivery research. The system can atomize and disperse liquid drugs into inhalable aerosols, and animals are exposed to an experimental chamber with a predetermined time and a certain concentration of a certain gas to complete the drug delivery process; it can also be used as a nose-only exposure system for animals exposure inhalation test. The system adopts an open design and is compatible with various aerosol generators, special gases, and pollutant sources. The nose-only restraint enables the animals to inhale the medicine only through the nose, avoiding the adhesion of the fur to the medicine and eliminating the effect of secondary administration by licking hair.
The high-frequency oscillation technology of microporous sieves is used in drug atomization, which replaces the traditional ultrasonic and air jet atomization. There are thousands of precise micropores in the center of the atomization head. During atomization, the microporous sieve ejects the liquid medicine as the aerosol through high-frequency vibration. Aerosols have a particle size of 1-5 microns, can effectively enter the alveoli, and are droplets facilitating deep lung deposition.
Product Features
Eliminate the effects of secondary oral administration
Reduce drug wastage
Simultaneous administration of multiple animals
Applications
Modeling and aerosol administration of respiratory diseases, such as bronchial asthma, pulmonary fibrosis, chronic bronchitis, and lung injury.