LabSolutions Insight Biologics is software for analyzing the characteristics of oligonucleotides using single quadrupole (SQ) mass spectrometers, quadrupole time-of-flight (QTOF) mass spectrometers, or MALDI mass spectrometers. Analyzing the characteristics of oligonucleotides involves the identification of impurities and sequence confirmation with modification positions estimated. Performing these analyses using a complicated mass spectrum requires a great deal of time. Additionally, using multiple software programs for the measurements and data analysis complicates the operations and puts considerable strain on the operator.LabSolutions Insight Biologics has been designed to resolve these issues.
With LabSolutions Insight Biologics, it is easy to configure the primary component sequence and data analysis parameters. Then using the sequence entered, the program can comprehensively identify chain length differences, nucleotide gaps, modifications, ion adducts, and other impurities. The molecular weights of the primary components and impurities are estimated with the MS1 spectrum, and the sequence is estimated from the fragment spectra of the impurities. Also, the sequence validity can be confirmed by visually checking the fragment coverage.
LabSolutions Insight Biologics is all-in-one LabSolutions series software. After measurements with LabSolutions, the data analysis is implemented automatically with the specified parameters, so when the measurements are started, everything up to the display of the analysis results is performed seamlessly.