Automatic DNA/RNA analyzer Tm

Tm analysis systems can accelerate the development process and improve the quality of oligonucleotide therapeutics. Control by LabSolutionsTM software enables compliance with ER/ES-related regulatory requirements and improves the efficiency of analyzing the thermal stability (Tm analysis) of nucleic acids. What is Tm Analysis System Tm analysis serves an important role in checking the thermal stability and sequence of nucleic acids. In Tm analysis, heat is applied to the nucleic acids in double-strands. Then, the change in absorbance (melting curve) that occurs as the temperature increases and the strands dissociate into single strands is measured. The melting temperature (Tm value) is determined as the temperature where the mole fractions of single and double strands are equal. LabSolutions, TMSPC and the Analytical Intelligence logo are trademarks of Shimadzu Corporation or its affiliated companies in Japan and/or other countries. Excel is either registered trademarks or trademarks of Microsoft Corporation in the United States and/or other countries. Features Reliable Data Integrity System Configuration Tm analysis system consists of the following. UV-Vis Spectrophotometer TMSPCTM-8i 8-cell thermoelectrically temperature controlled cell holder LabSolutions UV-Vis Tm software Data Integrity Tm analysis systems comprise a spectrophotometer, TMSPC-8i 8-cell thermoelectrically temperature-controlled cell holder, and LabSolutions UV-Vis Tm software. They can automatically determine Tm values based on melting curve measurements using the average method or derivative method.