The Serum Amyloid A (SAA) Assay* for use on Atellica® NEPH 630,* BN™ II, and BN ProSpec® Systems is designed to enhance diagnostic sensitivity for infections.
Parallel determination of CRP and SAA is useful in diagnosing inflammatory processes, especially viral infections, due to a strong rise in its blood concentration within a few hours.1,2
Recent studies show that SAA can be a prognostic marker for decline and death in COVID-19 patients.
Features & Benefits
The Serum Amyloid A (SAA) Assay* from Siemens Healthineers provides:
High specificity based on monoclonal antibodies
Fully automated testing for improved workflow
A broad initial measuring range (3–200 mg/L) that helps reduce the need for redilutions and supports economical reagent use
A complete kit, including reagent, calibrator, controls, and supplementary reagent (SCS Cleaner reagent available separately)
The ability to perform parallel determination of SAA and CRP, which can enhance diagnostic sensitivity for infections 2
Clinical Use
High sensitivity in diagnosis and monitoring of inflammatory processes.
Serum amyloid A (SAA) represents a protein family and is an acute-phase protein mainly produced by the liver in response to proinflammatory cytokines secreted by the activated monocytes/macrophage lineages.
Like C-reactive protein (CRP), SAA determination can be used in the diagnosis and monitoring of inflammatory and infectious processes. In contrast to CRP, SAA levels show a stronger response to viral infections, while CRP responds more strongly to systemic bacterial infections.