ChimeRMarker® automated chimerism analysis software integrates speed and accuracy with a biologist-friendly interface. The software can be used to monitor chimerism level in both an allogeneic stem cells transplant (SCT) or a hematopoietic stem cells transplant (HSCT), bone marrow transplant (BMT, post bone marrow engraftment), and cord and peripheral blood stem cells transplant (PBSCT) samples.
Complete Chimerism Detection, Long-term Monitoring, and Quantification in one program!
ChimeRMarker software provides:
Accurate, rapid genotyping and chimerism analysis with documented time savings of up to 85%
Automatically identifies donor and recipient peaks in post-BMT samples
Calculates percent chimerism and quality metrics for single donor or double donor cases
Easily appends for longitudinal monitoring post-BMT
Multi-lineage capabilities for chimerism analysis of T-cells, B-cells, and other cell type populations
ChimeRMarker software includes functions for comparison of samples at different time points to conduct longitudinal studies for monitoring each individual and a comprehensive chimerism analysis report. The chimerism analysis performs repetitive calculations (using published methods. Dr. Don Kristt).
ChimeRMarker software also has a linked maternal cell contamination (MCC) application. ChimeRMarker software is compatible with ABI®PRISM, Applied Biosystems® SeqStudio, Hiachi High-Tech Compact CE Sequencer DS3000, Promega Spectrum Compact CE Systems and Syntol Nanophore® 05 genetic analyzers, and custom primers or commercially available human identification chemistries for STR genotyping (including, but not limited to Identifiler®,