Solution reagent RiboGrip®

RNase inhibitorfor microbiologymulti-function

Exceptional stability – stable for up to 60 °C for 1 hour Unique high concentration formulation Efficient protection of RNA at low DTT concentrations Lyo-compatible glycerol free formulation available Description RiboGrip® RNase Inhibitor (220 U/µl) is an in silico-designed protein-based ribonuclease inhibitor, which inactivates RNase A, RNase B and RNase C. RiboGrip® inhibits the activity of ribonuclease A by noncovalently binding in a non-competitive mode at a ratio of 1:1. It is primarily used to prevent RNA degradation by contaminating RNases in various assays that use RNA sample materials, such as first strand cDNA synthesis, RT-(q)PCR, RT-LAMP, etc. RiboGrip® also includes a genetic modification - Stability TAG - Solis BioDyne’s proprietary and patented polypeptide stabilization technology [1]. Stability TAG makes RiboGrip® extremely tolerant to higher temperatures and enables room temperature shipping as well as effective use in assays requiring high incubation temperatures. Demonstrated through our in-house testing where RiboGrip® retains full activity after 1 hour incubation at 60 °C. Unique high concentration and glycerol free formulation is perfect for lyophilization! Click HERE to see our lyo-compatible RiboGrip®. Included in FIREScript® and SOLIScript® cDNA Synthesis Kits and Mixes, and in all SOLIScript® 1-step RT-PCR kits. Applications Preventing RNA degradation in variety of applications including: First-strand cDNA synthesis RT-PCR, RT-qPCR, RT-LAMP In vitro transcription and translation RNA isolation and purification RNA sequencing