Fully automated self-cleaning benchtop dissolution tester.
100% UNATTENDED - Run a series of dissolution tests in an unattended sequence.
100% TRACEABLE - Automatically execute and record all steps from vessel filling to self-cleaning of the dissolution tester.
100% REPRODUCIBLE - Perform all steps of the dissolution test the same way every time.
MEDIA - Automatic heating & degassing of up to 5 different media types.
FILTRATION - Powerful piston pumps to push through fine porosity filters for HPLC / UPLC analytical finish.
CLEAN - Highly effective & robust cleaning of all fluid paths that can be validated.
COLLECT - Automated sample collection in glass tubes, capped LC vials, or LC wellplates.
The AT MD is a fully automated dissolution tester that fits on your standard laboratory bench. It easily handles basket and paddle methods as well as sinkers including large Japanese sinkers. Once a sequence is started, the AT MD runs up to 8 unattended batches - from media preparation to self-cleaning of the system.
Up to 5 different media - including concentrates and media with surfactants - can be automatically heated, degassed, and dispensed into the vessels. Additionally, the AT MD can perform pH changes during tests and easily change media types between test runs. A gravimetric delivery system assures accurate and reproducible media dispensing. Various fill volumes in different vessels - from 250 mL to 1'000 mL - are possible, which makes the AT MD an ideal system for DoE studies.
The AT MD uses automated AutoLift™ cannulas to simultaneously withdraw samples. Individual vessel temperatures are recorded when sampling.