Flow-through cell dissolution testing system with integrated UV-Vis analysis of samples in real-time.
ANALYZE – Dissolution testing results can be viewed in real time as they are generated, reducing analysis time and costs
ADAPT – Test APIs, oral, topical and parenteral dosage forms reproducibly
PROGRAM – Define methods and specifications in one validated platform, using SOTAX Dissolution software
TEST – Run dissolution profiles based on programmed time points, flow rate and media changes with a complete traceability
RECORD – Allows complete traceability through user's right administration, audit trail, unlimited method programming and reporting
The capability to analyse the dissolved active immediately with a connected spectrophotometer, is the quickest way to get to the dissolution results. The CP pump will fill the flow cells connected to each dissolution vessel and the multi cell changer of the spectrometer will move to the appropriate position, that each vessel can be measured instantly. Combinations with different UV-Vis brands and types are available.
Dissolution testing is a supra-indicator of parameters monitored during the manufacturing of a dosage form. The CE 7smart apparatus 4 widens the design of experiment being the only compendial dissolution instrument allowing a reproducible testing of APIs, intermediates and final dosage forms. The CE 7smart gives relevant information from pre-formulation and characterization to IPC and QC testing.
Envisioned to mimic in-vivo conditions more accurately than beaker methods, the Flow-Through Cell technique was born to ambitiously push dissolution testing borders.