Colorectal cancer detection kit PC202301006

oncologySEPT9clinical

Septin is a family of highly conserved cytoskeletal protein genes in evolution. It has GTPase activity. The Septin9 gene in the family is involved in various physiological activities such as cell division, cell migration and DNA repair. Patients with colorectal cancer often have a certain degree of methylation in the promoter region of the Septin9 gene; this abnormal methylation will inhibit the tumor suppressor effect of the Septin9 gene, affect the occurrence and development of colorectal cancer. The sensitivity of Septin9 for screening colorectal cancer was 82.22%, which was significantly higher than that of CEA; the specificity was 89.09%, which was higher than that of FOBT. Septin9 detection has high sensitivity and specificity in various indicators of colorectal detection, and has the advantages of non-invasive, convenient sampling, and stable method. It can be used as an important auxiliary method for clinical diagnosis of colorectal cancer. DETECTION SIGNIFICANCE 1. Assist clinical early screening of colorectal cancer. 2. Assist clinicians to formulate intervention or control measures in time. ELIGIBLE POPULATION 1. Patients with chronic enteritis and family colon polyps. 2. People over 50 years old. FEATURES & ADVANTAGES 1. Accuracy and Reliability: Use pre-load PCR tube to effectively avoid cross-contamination. 2. Ease of Use: The process is standardized and the experimental procedure is simple. 3. Great Versatility: Validated on the most common qPCR machines with stable results. DETECTION PROCESS 1、Nucleic Acid Extraction 2、Modification 4、Amplification 5、Data Analysis