QUANTIFOIL® Holey Carbon supports are a flat film of carbon, 10-12 nm thick, on a cryo-electron microscopy (cryo-EM) grid. They provide a low-background sample support ideal for high-resolution cryo-EM data collection. The optimum grid for your project can be selected from a wide variety of hole shapes, sizes and spacings in combination with a range of base grid materials and mesh sizes. Grid options include standard square meshes as well as other arrangements and finder grid formats.
Circular
Ideal for high-resolution studies of biological macromolecules and other materials, round holes optimize the formation of a thin, even layer of ice to support a sample of interest. Select from our wide range of geometries depending on the characteristics of your sample and your imaging modality.
Square
Often used for applications where larger carbon-free areas are desired, square grids have less carbon support. They can be used with an additional thin carbon layer where samples need continuous support.
Multi A
With a repeating pattern of hole size, shape and spacing, Multi A foils are useful for particles of unpredictable size, for example liposomes, while the oval shape can aid in tomographic data collection.