H₂ :
Biomarker of microbial metabolism for the diagnosis of gastrointestinal diseases such as SIBO and carbohydrate maldigestion
Produced by H2-producing bacteria via microbial fermentation.
CH₄ :
Biomarker of microbial metabolism , especially for constipation and/or bloating
Produced by CH4-producing archaea or bacteria for H2 disposal.
H₂S*:
Biomarker of microbial metabolism for diagnosis of SIBO - Diarrhea
Produced by sulphate-reducing bacteria via H2 consumption.
Clinical Significance
Lactulose/Glucose Breath Test: Diagnose Small Intestinal Bacterial Overgrowth(SIBO)
Lactose/Fructose Breath Test: Diagnose Carbohydrate Maldigestion
Test Preparation - 12 Hour Fasting Period
Start-up Time Less than 30 min as Countdown in the Software
Sampling Offline Sampling Method, Home Breath-test Kit
Analysis 5 Measurements: H2, CH4, H2S*, 02, CO2; Results in 60-100 sec
Quality Control
Control of Dead Space Volume by Body Weight
Normalization by Exhaled O2/CO2
Indications Gastroenterology: IBS, IBD, H.p Infection, GastrointestinalTumor, Polyps, Pancreatic/Liver Diseases Metabolomics/Endocrinology: Diabetes, Obesity, Metabolic Disorder, Osteoporosis, Gout Cardiology: Cardiovascular Diseases, Parkinson's Disease, Depression, Autism