SARS-CoV-2 is an enveloped positive-sense RNA virus that causes COVID-19. The spike (S) spike protein is located on viral membrane and gives the name of coronavirus family via resembling a crown-like structure. Main function of S-protein is the binding to recognition protein, ACE2, on host cells and facilitation of viral and cell membranes. S-protein is composed of two domains: S1 and S2 domains.
Synonyms:
SARS-CoV-2 Spike ProteinSARS-CoV-2 S-protein
Origin Species:
SARS-CoV-2
QC testing:
Purity: > 90%
Endotoxin Content: None
Properties:
Calculated mass: 137.1 kDa
Apparent mass (SDS-PAGE): ~200 kDa
Recombinant Source: HEK293
Sequence: NCBI (YP_009724390.1), Uniprot (P0DTC2) – Furin site mutated to A, K986P and V987P for stabilization
Tag/Conjugation: C-terminal Thrombin cleavage, T4 foldon trimezation domain and C-terminal 6xHistidine Tag (HHHHHH)
Formulation: 1x PBS pH=7.4, 10% Glycerol
Physical Appearance: Liquid, transparent.
Applications:
SDS-PAGE, Western blotting (WB), serological ELISA and lateral flow immunoassays (LFIA),
Shipping:
Shipped as with ice blocks
Storage/Stability:
Store as at – 20 ˚C in aliquots upon arrival. Do not freeze/thaw repeatedly.
Note:
Synbiotik’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.