Protein reagent AG-0102

solutionlaboratoryliquid

SARS-CoV-2 is an enveloped positive-sense RNA virus that causes COVID-19. The spike (S) spike protein is located on viral membrane and gives the name of coronavirus family via resembling a crown-like structure. Main function of S-protein is the binding to recognition protein, ACE2, on host cells and facilitation of viral and cell membranes. S-protein is composed of two domains: S1 and S2 domains. S1 domain contains a vital subdomain for ACE2 binding namely, receptor binding domain (RBD) and N-terminal domain. Neutralization antibodies are mostly targeted to S1 domain rather than S2 domain. Also, S1 domain is less conserved part of Spike proteins among human coronaviruses. Synonyms: SARS-CoV-2 Spike Protein S1 Domain, SARS-CoV-2 S-protein S1, SARS-CoV-2 S1, SARS-CoV-2 S-S1 Origin Species: SARS-CoV-2 Endotoxin Content: None Properties: Calculated mass: 75.1 kDa Apparent mass (SDS-PAGE): ~ kDa Recombinant Source: HEK293 Sequence: NCBI (YP_009724390.1), Uniprot (P0DTC2) – [Met1-Ser683] Tag/Conjugation: C-terminal 6xHistidine Tag (HHHHHH) Formulation: 1x PBS pH=7.4, 10% Glycerol Physical Appearance: Liquid, transparent. Applications: SDS-PAGE, Western blotting (WB), serological ELISA and lateral flow immunoassays (LFIA) Shipping: Shipped as with ice blocks Note: Synbiotik’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.