SARS-CoV-2 is an enveloped positive-sense RNA virus that causes COVID-19. The spike (S) spike protein is located on viral membrane and gives the name of coronavirus family via resembling a crown-like structure. Main function of S-protein is the binding to recognition protein, ACE2, on host cells and facilitation of viral and cell membranes. S-protein is composed of two domains: S1 and S2 domains. S1 domain contains a vital subdomain for ACE2 binding namely, receptor binding domain (RBD). Solely RBD can binds ACE2 protein.
Synonyms:
SARS-CoV-2 Spike Protein Receptor Binding Domain, SARS-CoV-2 S-protein RBD, SARS-CoV-2 RBD, SARS-CoV-2 S-RBD
Endotoxin Content: None
Properties:
Calculated mass: 25.9 kDa
Apparent mass (SDS-PAGE): ~32 kDa
Recombinant Source: HEK293
Sequence: NCBI (YP_009724390.1), Uniprot (P0DTC2) – [Arg319-Phe541]
Tag/Conjugation: C-terminal 6xHistidine Tag (HHHHHH)
Formulation: 1x PBS pH=7.4, 10% Glycerol
Physical Appearance: Liquid, transparent.
Applications:
SDS-PAGE, Western blotting (WB), serological ELISA and lateral flow immunoassays (LFIA)
Shipping:
Shipped as with ice blocks
Note:
Synbiotik’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.