Solution reagent CALiaGold

laboratoryESRliquid

Home sampling with improved ease of use Simplified laboratory workflow Just one step from sample collection to analysis No contamination risk in the laboratory Fast and fully automated quantitative immunoassay Calprotectin is a protein mainly found in the cytoplasm of neutrophilic granulocytes. In cases of gastrointestinal (GI) inflammation, neutrophils migrate through the intestinal wall and calprotectin is released due to degranulation. It accumulates in the faeces and is excreted from the body. The concentration of calprotectin directly correlates with the number of neutrophils in the intestinal lumen, making it an ideal biomarker for GI inflammation. The determination of faecal calprotectin (fCal) is a non-invasive option to assess localised inflammation. Being highly sensitive for the detection of GI inflammation, it helps in the differential diagnosis of inflammatory bowel diseases (IBD) and irritable bowel syndrome (IBS). The biomarker fCAL outperforms general inflammation markers such as C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR) since it is more sensitive and more specific. CALiaGold is the complete solution for the automated quantitative determination of calprotectin in human faeces. The particle-enhanced turbidimetric immunoassay (PETIA) is based on the agglutination reaction between latex particles coated with antibody and the antigen in solution. It can be run, along with the FOB Gold test, on your dedicated faecal analyser (SENTiFIT 270 Analyser or SENTiFOB Analyser). The CALiaGold system comprises a tube for sample collection and a next-generation immunological latex reagent for the detection of calprotectin.