Synthetic bone substitute NANOGEL®

for orthopedic surgeryfor dental sugeryputty

Thanks to its composition and structure, NANOGEL® is a synthetic bone substitute similar to bone tissue. This product is an absorbable bone void filler that provides a support for bone ingrowth. NANOGEL® offers to surgeon various possibilities of use; percutaneous surgery to fill closed bone defects or open surgery. ADVANTAGES Osteoconductive Biocompatible Synthetic Absorbable Injectable gel Bone void filler Percutaneous use INDICATIONS NANOGEL® is indicated for the filling of bone defects due to bone injury (such as trauma, disease) or surgical procedure (such as arthrodesis, intervertebral cage filling). PROPERTIES COMPOSITION • Hydroxyapatite (Ca5[PO4]3[OH]) & Water (H2O) • Particles between 100 nm to 200 nm • Specific surface higher than 80 m²/g SYNTHETIC • Free from organic phase • No immunological risk INJECTABLE Syringe ready to use – Luer Lock connection STABLE Non hardening gel which remains pasty in situ ABSORBABLE Crystals of HA resorb in minimum one year* BIOCOMPATIBLE Compliant to ISO 10993-1** OSTEOCONDUCTIVE In vivo studies have shown a cellular invasion and high bone ingrowth within months after implantations*** * Lifetime report SG150719 – Internal report ** Biological Risk Assessment Report NANOGEL® 097/3/PERB – Internal report *** Rapport CIT Animal studies n°08-02 – Internal report