Measure circadian activity
Enrichment – increase animal welfare
Control access by time, distance run or operant performance
Synchronize wheel data with metabolic parameters
Workload option – study motivation & muscle physiology
Complex wheel – evaluate fine motor skills
Wheel running is widely used to assess voluntary physical activity in rodents. It is ideally suited to study circadian activity. Running wheels might also serve as environmental enrichment to improve animal welfare during long-term experiments
TSE Running Wheels for rats and mice are suspended from the home cage lid, leaving maximum living space for the animal and allowing combination with ActiMot3 frames for a comprehensive evaluation of the total activity.
The optional Motor Skill drum features removable rods to create an irregular rod pattern. This complex wheel has been proven to be a powerful new tool to detect motor deficits much earlier as compared to standard tests such as the RotaRod.
Use the Enable/Disable function to control access to wheel running by time and distance – or by taking any other parameter measured with PhenoMaster components such as bodyweight or food consumption into account. Couple the wheels to Operant Walls to use wheel running as reinforcement or as a prerequisite to earn food reward.
When combined with TSE PhenoMaster Indirect Calorimetry or Food intake modules wheel activity can be easily synchronized with metabolic parameters.