As the energy delivered by the radiofrequency generator meets resistance in the tissue, heat is produced. The amount of heat will vary depending on the amount of current, the resistance levels in the targeted tissue and the characteristics of the electrodes. Initial collagen denaturation within these thermally modified deep tissues explains the immediate tissue contraction is achieved from the first treatment. Subsequently neocollagenesis, as a natural healing response to the denaturized collagen, further tightens the dermal tissue and reduces wrinkles. This appears 4-6 months after treatment. A longterm effect is achieved within 6-8 sessions.