Malaria detection kit

aldolasePlasmodiumblood

Malaria is a severe mosquito-borne disease caused by 5 species of parasites of the Plasmodium genus (P. vivax, P. falciparum, P. malariae, P. ovale, and P. knowlesi), Plasmo- dium falciparum infection is the one most associated with severe Malaria and can even lead to death. Malaria is char- acterized by high fevers, shaking chills, and flu-like illness. Early diagnosis is crucial for treatment and controlling the infection’s spread in the community. Malaria is treatable and curable if diagnosed quickly and treated appropriately, and delay in diagnosis and treatment is a leading cause of death in malaria patients The five plasmodium species share a ‘Pan-Plasmodium’ en- zyme called aldolase that is commonly investigated to con- firm a malaria infection in lateral flow immunoassays. In the case of P. falciparum, the histidine-rich protein II (HRP-II) is widely present in P. falciparum infections and can be detected in the blood during the infection. INTENDED USE Turklab’s Malaria Test is a rapid chromatographic immu- noassay for the qualitative detection of Malaria as well as distinguishing the causing parasite species by detecting pan-plasmoduim aldolase antigen and P. falciparum spesi- fic HRP-II antigen in whole blood. • Verified no cross reactivity with with HAMA, RF, HBsAg, HBsAb, HBeAg, HBeAb, HBcAb, Syphilis, HIV, HCV, H. Pylori, MONO, CMV, Rubella and TOXO positive controls. • Wide range of samples can be used, plasma, serum, capil- lary blood, or venous blood. • Small volume of sample (5 ul) is needed.