Diagnostic Kit for the Quantitative Determination of Cardiac Troponin I (Fluorescence Lateral Flow Immunoassay)
This kit is used for the in vitro quantitative determination of Cardial Troponin (cTnI) concentration in human serum/plasma or whole blood samples.
Cardiac troponin I(cTnI), a 24kDa subunit of the troponin complex composed of 209 amino acids, regulates actin and myosin interactions by regulating the activity of Ca2+ on rhabdomyosin atpase.After myocardial injury, the cTnI complex was released into the blood and began to rise in the blood after 4 – 6 hours. The increased cTnI can remain in the blood for a long time (6 – 10 days), thus providing a longer test period. cTnI has high myocardial specificity and sensitivity and is one of the markers of myocardial infarction. In laboratory diagnosis, the detection of myocardial enzyme is one of the important indices for diagnosis of acute myocardial infarction (AMI), the CK and CK – MB testing was considered the most powerful basis for the diagnosis of AMI, the detection of myocardial enzyme spectrum, however, there are still many deficiencies, the reason is that the sensitivity and specificity is poorer, and cardiac troponin I (cTnI) can detect tiny myocardial injury, become one of the strongest markers of myocardial cell damage sensitivity and specificity, is recognized as a rapid diagnosis of acute impatient infarction (acute myocardial infarction. AMI) and acute coronary syndrome (ACS), as well as major markers that assist in risk stratification and reflect prognosis of ACS.