Infectious disease test kit ODZ-450

for serologyIgGvirus

Immunoenzymatic kits for the semiquantitative / quantitative detection of specific IgG antibodies against polyomavirus JC antigens in human serum and plasma. Recombinant antigens used in the kit do not cross-react with other polyomaviruses (polyomavirus JC, Merkel cell polyomavirus). The kit is used for the serological diagnostics of diseases caused or associated with BKV (e.g. BK-viral nephropathy, haemorrhagic cystitis, urethral stenosis, infections of upper and lower respiratory tract mainly in immunodeficient patients) and for the risk assessment of infection transmission and subsequent complications in graft acceptors. Anti-BKV antibodies are present in 50% to 80% of adult population. Primoinfection occurs mostly during childhood and in most of the cases it is asymptomatic or brings on an acute respiratory disease and then continues to the latent phase, which is characterised by long-term presence of anamnestic IgG antibodies in serum. In latently infected persons the virus can repeatedly reactivate or they can be re-infected by other BKV serotype. Reactivation/reinfection can be accompanied by temporary viremia or viruria; Polyomavirus JC ELISA-VIDITEST anti-JVC IgG kit is intended for the detection of anti-polyomavirus JC specific IgG antibodies in human serum and plasma. From 50% to 60% of population is infected by polyomavirus JC (JCV) during childhood. Infection is without any symptoms and later continues to the latent phase, which is characterised by long-term persistence of anamnestic IgG antibodies in serum.