ELISA-VIDITEST and IF-VIDITEST anti-VZV kits are intended for the diagnosis of diseases induced or associated with VZV infection, such as varicella (chickenpox), herpes zoster (shingles) and the disease complications (pareses, neuropathies, encephalitis, myelitis, cerebellitis, pneumoniae, uveitis) and generalized infections in immunocompromised patients. The kits can also be utilized for differential diagnosis of neuroinfections, infections of eye and skin and exanthematous diseases.
VZV-specific IgG antibodies have anamnestic character, can be utilized for determination of individual immune status. Their significant increase in paired serum samples may indicate active infection. VZV-specific IgM and IgA rise in the course of active infection (both primary infection and reactivation) and disappear in convalescence phase. In some cases, they may persist in patient´s serum several weeks or months. Determination of VZV IgG avidity is useful to distinguish between primary and past infection or VZV reactivation.