Genetically determined enzyme and transporter deficiencies may cause hereditary intolerance to common dietary sugars. ViennaLab assays identify the most frequent genetic variations responsible for sugar intolerance.
Lactose intolerance is a frequent autosomal recessive condition causing diarrhea, nausea and flatulence. The disease is strongly associated with genetic variants regulating the expression of the lactase (LCT) gene.
Hereditary fructose intolerance is an autosomal recessive disorder caused by variants of the aldolase B (ALDOB) gene. Affected subjects suffer from abdominal pain, vomiting,
hypoglycemia, and unless fructose-containing food is strictly avoided may even die from organ damage.
ViennaLab assays are available for the detection of two LCT and four ALDOB genetic variants.