Inflammatory disease test kit

for antigen Dfor calprotectinplasma

For professional in vitro diagnostic use only. Professional trained in turbidimetric techniques. INTENDED USE Vitassay Calprotectin –Turbidimetric Assay- is a rapid Turbidimetric assay for the quantitative detection of human calprotectin in human solid stool samples. Simple, non-invasive and highly sensitivity assay for the presumptive diagnosis of human calprotectin, which might be useful for the diagnosis of inflammatory gastrointestinal disorders. This product is optimized for several automated analyzer. The results should be used to differentiate between IBD patients with inflammation from IBD patients without inflammation and from with irritable bowel syndrome INTRODUCTION Calprotectin is a 36 KDa neutrophil cytosolic protein with antimicrobial properties. Increased concentration of this protein in stool samples is tightly associated to bowel inflammation. This protein remains stable in faeces for up to 7 days at room temperature, becoming it an ideal disease marker. Calprotectin releasing is associated to leukocytes activation, giving increased levels in plasma, urine or stools as a consequence of disease in the relevant organ(s). PRECAUTIONS Specimens should be considered as potentially hazardous and handle in the same manner as an infectious agent. Avoid contamination errors, follow proper work procedure. • The reagents after use should be discarded in a proper biohazard container after testing. Reagents contain preservatives. Avoid any contact with the skin or mucous membrane. Consult safety data sheet, available on request.