Rapid pneumonia test

for antigensLegionella pneumophilaurine

Vitassay Legionella is a rapid one step immunochromatographic assay for the qualitative detection of Legionella pneumophila in human urine samples. Simple, non-invasive and highly sensitive screening assay to make a presumptive diagnosis of legionelosis in infected humans. INTRODUCTION Legionella species cause 2 clinical syndromes, known as Legionnaires disease and Pontiac fever. Legionnaire disease is an acute, serious, and sometimes lethal pneumonia, whereas Pontiac fever is generally a self-limited, non-pneumonic, influenza-like condition. Legionella pneumophila has been increasingly recognized as a significant cause of sporadic and epidemic community acquired pneumonia in all age groups and in both healthy and immunosuppressed hosts. PRINCIPLE Vitassay Legionella is a qualitative immunochromatographic assay for the detection of Legionella pneumophila (L. pneumophila) in human urine samples. The test line zone of the nitrocellulose membrane is pre-coated with polyclonal antibodies against L. pneumophila. During the process, the sample reacts with the antibodies against L. pneumophila, forming conjugates. The mixture moves upward on the membrane by capillary action. If the sample is positive, antibodies present on the membrane (test line) capture the conjugate complex and a red line will be visible. Although the sample is positive or negative, the mixture continues to move across the membranes and the blue control line always appears. The presence of this blue line (in the control zone (C)) indicates that sufficient volume is added; proper flow is obtained and serves as an internal control for the reagents.