Vitassay Norovirus is a rapid one step immunochromatographic assay for the qualitative detection of norovirus genogroups I and II (GI and GII) in human stool samples. Simple, non-invasive and highly sensitive screening assay to make a presumptive diagnosis of norovirus (GI and GII) infection.
NTRODUCTION
Noroviruses are a group of no enveloped single-stranded positivesense RNA viruses classified in the family Caliciviridae. Norovirus can infect humans via multiple routes, including the oral route, transmitted through contact with fecal matter or aerosolized vomitus from infected people, as well as contaminated surfaces, food, or water. After incubation period 12 to 48h, Norovirus illness is characterized by projectile vomiting, no bloody diarrhea, nausea, abdominal cramps, and low-grade fever. Some persons might experience only vomiting or diarrhea. In healthy individuals, the duration of symptoms is usually not longer than 48 h, and the disease is selflimiting in most patients. However, young children and the elderly are at increased risk for more-severe and prolonged illness leading hospitalization, while the disease is increasingly recognized as an important cause of chronic gastroenteritis for immunocompromised patients. Although Norovirus can be detected in rectal swabs and vomitus, whole-stool samples are the preferred clinical specimen for the detection of Norovirus because they contain a higher quantity of virus.
PRINCIPLE
Vitassay Norovirus is a qualitative immunochromatographic assay for the detection of norovirus genogroups I and II (GI and GII) in human stool samples.