Vitassay Giardia is a rapid one step immunochromatographic assay for the qualitative detection of giardia in human stool samples.
Simple, non-invasive and highly sensitive screening assay to make a presumptive diagnosis of giardia infection (giardiasis).
INTRODUCTION
Giardia is a common cause of acute gastroenteritis in humans and many animal species across the globe. Giardia nowadays is recognized as the most common parasitological cause of diarrhea, with 280 million infections per year. The main symptoms is watery, foul smelling diarrhea, often accompanied by nausea, abdominal cramps or gurgling, bloating and weight loss. Symptoms of variable severity may persist for weeks. Additionally, international travelers returning from endemic areas and asymptomatic carries may play an important role in the spreading of these infections. Furthermore, chronic giardiasis can lead to malabsorption and failure to thrive in children increasing the disease burden due to this infection. Although Giardia does cause disease, it can also be asymptomatic in humans and animals. Since it has a fecal-oral transmission cycle and is contracted by ingestion of contaminated water or food or by person-to–person contact, the highest disease burden is found in areas where sanitary conditions are poor.
PRINCIPLE
Vitassay Giardia is a qualitative immunochromatographic assay for the detection of giardia in human stool samples. The test line zone of the nitrocellulose membrane is pre-coated with monoclonal antibodies against giardia. During the process, the sample reacts with the antibodies against giardia, forming conjugates. The mixture moves upward on the membrane by capillary action.