Enzyme reagent Tin(exo-) LF

DNA polymerasefor isothermal amplification

OptiGene’s patented thermostable DNA polymerase for amplification reactions requiring an initial heat-denaturing step. Extreme thermostability and strong strand-displacement activity enable applications unachievable in a single, closed-tube reaction using alternative isothermal enzymes. Key features: Extreme thermostability* ( < 98ºC ) Superior strand-displacement activity 5’-3’ exonuclease minus 3’-5’ exonuclease minus *no loss of activity is observed in a LAMP reaction following 5 minutes @ 95ºC step. Advantages of HD-LAMP: Template denaturation step at 95ºC prior to amplification has been shown to increase target sensitivity1 Increased primer specificity – reduces false-priming that may occur at lower temperatures. Simple template extraction (cell-lysis). Sample heat-lysis, amplification and detection in a single tube.