IgM/lgG Combined Antibody Test for COVID-19 is immune
chromatography based. The test card contains (1) colloïdal
gold-labeled recombinant novel corona virus antigen and
quality control antibody colloidal gold marker, two détection
lines (G and M lines) and one quality control line (C) fixed on
a nitrocellulose membrane. M is fixed with monoclonal
anti-human IgM antibody for detecting the novel corona virus
IgM antibody. G is fixed with monoclonal anti- human IgG
antibody for detecting the novel corona virus IgG antibody.
The quality control antibody is fixed on the C line.
When an appropriate amount of test sample is added to the
sample well of the test cassette, the sample will move
forward along the test card via capillary action. If the sample
contains IgM antibody, the antibody will bind to the colloidal
gold- labeled novel corona virus antigen. The
antibody/antigen complex will be captured by the anti-human
IgM antibody immobilized on the membrane, forming a red M
line and indicating a positive resuit for the IgM antibody.
If the sample contains IgG antibodies, the antibody will bind
to the colloidal gold-labeled novel corona virus antigen and
the antibody/antigen complex will be captured by the
antibody immobilized on the membrane, forming a red G line
and indicating a positive resuit for the IgG antibody.