Molecular diagnostic detection kit YZYMT-007

for genetic mutationsgeneticblood

Human CYP2C9 and VKORC1 Gene Detection Kit (PCR-Fluorescent Probe Method) This product is used for the qualitative detection of polymorphism of CYP2C9 CYP2C9*3 and VKORC1 VKORC1-1639G>A in whole blood samples. Warfarin is the earliest, most widely used oral anticoagulant in clinical practice, and has been used in the anticoagulation treatment of many diseases, such as primary and secondary prevention of venous thromboembolic disease (VTE), prevention of thromboembolism in atrial fibrillation. However, their clinical efficacy and adverse effects vary greatly, and the dosage is difficult to control. However, the clinical efficacy and adverse effects vary greatly, and the dose is difficult to control, especially in the early stage of anticoagulation therapy with warfarin, which may lead to serious bleeding complications. It is estimated that 15.2% of patients taking warfarin experience bleeding side effects each year, of which Fatal hemorrhage accounts for 3.5% of cases, and the difference in stable warfarin dose between individuals can be more than 20 times. In 2007, the FDA updated the instructions for warfarin to emphasize the use of genetic testing to adjust the initial dose of warfarin for individual patients, thereby optimizing warfarin use and reducing the risk of bleeding.