YZY Rapid FISH Probes -- Leukemia
Leukemia is one of the most common cancer. FISH has important clinical significance in the diagnosis, treatment, prognosis and MRD detection of hematological malignancies,meanwhile FISH has been recommended by guidelines such as NCCN for the diagnosis and treatment of hematological malignancies, including acute and chronic leukemia, myelodysplastic syndrome (MDS), multiple myeloma (MM),and other hematological malignancies.
Probe Names:
1. MYC(8q24) Gene Amplification
2. KMT2A(11q23)Gene Deletion
3. GLI1(12q13) Break Apart
4. NUP98(11p15) Break Apart
5. Chr12/D13S25 Gene Deletion
6. 11q23/DLEU1 Gene Deletion
7. ATM/p53/13q14/RB1/CSP12 Gene
8. ABL1/ABL2/PDGFRB/CRLF2/JAK2 Break Apart
9. i(17q)Gene
10. p53/[CCND1/IGH]/ATM/CSP12/D13S25 Gene
11. FGFR1/PDGFRA/PDGFRB Break Apart
12. P53 Gene Deletion
13. MYC Break Apart
14. BCL2/IGH Gene Fusion
15. Chr8 Centromere
16. JAK2 Break Apart
17. ATM Gene Deletion
18. PDGFRB Break Apart
19. CCND3/IGH Gene Fusion
20. RARA Break Apart
21. IGH Break Apart
22. CHIC2(PDGFRA Break) Gene Deletion
23. Chr12 Centromere
24. 7q
25. AML1 Break Apart
26. ETV6/AML1 Gene Fusion
27. ETV6 Break Apart
28. KMT2A(MLL)Break Apart
29. 6q
30. ASS(9q34) Gene
31. CBFB/MYH11 Gene Fusion
32. EVI(3q26) Break Apart
33. CDKN2A(9p21) Gene
34. CBFB Break Apart
Product Application
Auxiliary diagnosis: AML1-ETO acute myeloid leukemia, M2 type
Guiding medication: BCR-ABL , Imatinib
Assess prognosis: AML1/ETO for minimal residual monitoring