hs-cTnI Rapid Quantitative Test (Chemiluminescence Immunoassay) is used for in vitro quantitative detection of the high sensitivity cardiac troponin I (hs-cTnI) concentration in human serum, plasma that contains heparin /EDTA and other anticoagulants and venous whole blood samples, mainly used for auxiliary diagnosis of cardiac diseases.
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Application
Cardiac troponin I (cTnI) is a protein with a molecular weight of 37 kDa and is a subunit of the troponin complex involved in theregulating muscle contraction.
Under normal conditions, the level of peripheral blood cTnI is low. However, when acute myocardial infarction (AMI) or local ischemic injury occurs, its concentration rises rapidly due to its small molecular weight, allowing for its quick release into the human bloodstream.
The high sensitivity of cTnI assays makes them very effective in identifying myocardial injury, allowing them to be clinically distinguished from skeletal muscle damage caused by surgery, trauma, overexertion, or muscle disease.
The quantification of cTnI concentrations in human serum, plasma, and venous whole blood samples is primarily used as an aid in the diagnosis of acute myocardial infarction (AMI). The measurement of cTnI is a sensitive and specific marker of myocardial cell injury, making it a valuable tool in the evaluation and management of patients with suspected or known acute coronary syndromes.