hs-cTnT Rapid Quantitative Test (Chemiluminescence Immunoassay) is used for in vitro quantitative detection of the high sensitivity cardiac isoform of TnT (hs-cTnT) concentration in human serum, plasma that contains heparin /EDTA and other anticoagulants and venous whole blood samples, mainly used for auxiliary diagnosis of cardiac diseases.
Product Detail
Application
The cardiac isoform of troponin T (cTnT) is widely used as a marker of myocardial cell injury. In humans, the cardiac troponin T is encoded by the TNNT2 gene. The major isoform found in normal adult human heart tissue (isoform 6 or TnT3) is 287 amino acids long with a calculated molecular weight of 34.6 kDa.
cTnT has the same release kinetics into the bloodstream and the same sensitivity for minor myocardial injury as cardiac troponin I (cTnI). In the blood of patients with acute myocardial infarction (AMI), high-sensitivity cTnT (hs-cTnT) is often found in a free form, whereas cTnI is mostly found in a complex with troponin C (TnC).
The detection of cTnT in the blood is a sensitive and specific indicator of myocardial cell injury, making it a useful biomarker for the diagnosis and management of various cardiac conditions, including AMI.
Features
Smart - Photosensitive and Luminescent Microspheres
Rapid - Whole Blood Sample Type Supported & No Centrifuge Needed
Convenient - Room Temperature Storage & Minimal sample consumption
Clinical significance
Early Diagnosis of Acute Myocardial Infarction (AMI)
Risk Stratification for Acute Coronary Syndromes (ACS)
Monitoring and Serial Measurements
Rule-Out of Myocardial Infarction
Assessment of Chest Pain in the Emergency Department