The C-reactive protein(CRP) is synthesized by the liver in response to interleukin-6 and is well known as one of the classical acute-phase reactants. It is used as a marker of inflammation and cardiovascular diseases(C-VD). Biotime CRP test includes hs-CRP and normal CRP test parameters which has a wider test range.
Clinical Significance
CRP is used mainly as an inflammation marker. Apart from liver failure, there are few known factors that interfere with CRP production.
Normal levels increase with aging. Higher levels are found in late pregnant women, mild inflammation and viral infections (10–40 mg/L), active inflammation, bacterial infection (40–200 mg/L), severe bacterial infections, and burns (>200 mg/L).
CRP cut-off levels indicating bacterial from non-bacterial illness can vary due to co-morbidities such as malaria, HIV, and malnutrition, and the stage of disease presentation.