Introduction
Testosterone(17β-hydroxyandrost-4-en-3-one) is an anabolic steroid synthesized primarily by Leydig cells in the testes of male, the ovary of female, and adrenal glands of both sexes[1]. It is synthesized from cholesterol, androstenediol, Dehydroepiandrosterone(DHEA), progesterone, and pregnenolone acting as some of the intermediate substrates. Testosterone level in male increase 10 to 20-fold during puberty, driving the physiological changes associated with male puberty. It also exerts a powerful, wide-ranging influence over emotional well-being, sexual function, muscle mass and strength, energy, cardiovascular health, bone integrity, and cognitive ability throughout a man’s entire life. In the blood only 1% to 15% of testosterone molecules are free form or biologically active form. The remaining testosterone molecules are bound to serum proteins.
Advantages
The first domestic hormone testing project on POCT platform.
Clinical Significance
✔ Help in the diagnosis of testicular dysfunction
✔ Helps to evaluate female hirsutism, hair loss and menstrual abnormalities
Application
Laboratory, Outpatient, Gynecology, Endocrinology, Reproductive Center