Introduction:
The creatine troponin complex, formed by cardiac muscle creatine troponin I (cTnI), troponin T (TnT) and troponin C (TnC), can adjust the interaction between actin and myosin. The concentration of cTnI is rare low in healthy human blood. [1-3].
Creatine Kinase(CK) is a dimer existing as three isoenzymes. CK mainly exists in skeletal muscle, cardiac muscle and brain tissue. There are three types of isoenzymes, including BB (brain type), MM (skeleton-type) and MB(hybridization type). Thus CK-MB is regarded as a marker for acute myocardial infarction. [4-5]
Myo is a plasmosin of low molecular weight, whose speed released is faster than other label of heart muscle when the heart is hurt. Therefore, Myo is regarded as a marker for early acute myocardial infarction[4-5].
Advantage:
1. Equipped with special dropper consumables, the operation is easier and more suitable for clinical use
2. Low sample requirements: whole blood can be processed without centrifugation
3. 3 in 1 (cTnI/CK-MB/Myo) detections improve the sensitivity and accuracy of results, and reduce misdiagnosis caused by window reasons
Clinical significance:
1. 3 in 1 (cTnI/CK-MB/Myo) detection has high sensitivity, better specificity, and more accurate results
2. Assess the area of myocardial infarction, detect reperfusion and recurrence of myocardial infarction, etc.
3. As an important indicator of brain injury, nervous system disease, carbon monoxide poisoning diagnosis and treatment effect evaluation
Intended use:
ICU, Respiratory Medicine, Emergency department, Cardiology, Laboratory, emergency car